Name: Nadjet Cornejal, Claudia Melo
Mentor Name: Dr. Jose Fernandez Romero & Dr. Adolfina Koroch
Abstract: Guava (Psidium guajava) is a small tree from the Myrtaceae family native to Central and South America. Scientists have suggested that chemicals isolated from the guava plant can have antimicrobial and anti-inflammatory properties. We performed preliminary studies to determine if a guava leaves extract has antiviral activity against herpes simplex type 1 (HSV-1). For this purpose, the XTT colorimetric assay was used to estimate cytotoxicity (toxicity in cells) while the plaque-reduction assay was used to test the anti-HSV-1 activity. Our results suggest that we have a selective antiviral activity with a therapeutic index higher than 750. This result warrants further evaluation of the potential use of this extract to treat HSV-1 infections.
Luis Melo
Excellent research with unexpected results, thinking that the researchers used commercial guava leafs.
As they say in their presentation, it’s worthy to continue the research, this time using natural samples and not commercial guava leafs. Probably using samples not industrially treated, the results can be really impressive.
Good Job for both Researchers and their mentors!!!