For about 20 years, the US has been struggling with rising rates of use for particular types of drugs – opioids. These drugs interact with opioid receptors in the brain and include prescription pain medications and illegal drugs like heroin. In particular, one of the dangerous possible affects of opioid use is overdose and death.
Most states in the US are struggling with this problem. See a map with rates here – https://www.drugabuse.gov/drugs-abuse/opioids/opioid-summaries-by-state. This epidemic has evolved over time from overuse and misuse of prescription pain medication, to illicit heroic use, and the third wave of synthetic opioid use (like fentanyl).
There are some medications available for opioid use disorder, including milder opioids like methadone. Overdose deaths can be prevented with an opioid antagonist called naloxone. Government agencies are also working on preventing opioid addiction, limiting the use of prescription pain medications, and helping people find treatment options.